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Jelovac N, Sikiric P, Rucman R, Petek M, Marovic A, Perovic D, et al

Improper Storage (Pre- and Post-Reconstitution): Storing lyophilized powder in a hot car or leaving the reconstituted solution on the benchtop for a week are both recipes for degradation

Another study published in the Journal of the American Geriatrics Society found that B12 supplements improved memory and cognitive function in older adults with mild cognitive impairment

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Yes, in some cases, people are trained to give themselves subcutaneous injections of Vitamin B12

Wang L, Almeida LEF, Spornick NA, Kenyon N, Kamimura S, Khaibullina A, Nouraie M, Quezado ZMN (2015) Modulation of social deficits and repetitive behaviors in a mouse model of autism: the role of the nicotinic cholinergic system