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Mimics GLP-1: As a GLP-1 receptor agonist, Rybelsus mimics the effects of the naturally occurring hormone glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels, promotes insulin secretion, and reduces appetite, potentially contributing to weight loss

This can result in individuals eating less and, over time, losing weight

and when undergoing imaging studies that require fasting preparation

Treatment response : As per NICE guidance, assess response after 6 months and continue only if adequate benefit is demonstrated (HbA1c reduction of at least 11 mmol/mol [1%] and/or 3% weight loss from initial body weight)

Pricing tends to track the dose, which is one more reason to avoid climbing higher than you need

When first introduced, these name brands could cost $1,000+ per month without insurance