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Moreover, the positive correlation of testicular susceptibility index with sperm 8-OHdG content, testicular 8-OHdG and MDA content observed in our study suggest that impaired first-line enzymatic antioxidant activity in testis could reflect oxidative DNA damage in both sperm and testis

TRIUMPH-1 (NCT05929066) will look at the efficacy and safety of retatrutide in people with overweight/obesity without T2D and will include subsets of participants with knee osteoarthritis (OA) or OSA

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