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GLP-1 is mainly produced in the enteroendocrine L cells located in the distal intestine exerting its effects through binding to the GLP-1 receptors (GLP-1R) expressed in the pancreas, heart, blood vessels, gastrointestinal tract (GIT), kidney, lung, breast, and central nervous system [11],[12]

The Functional Medicine View of Rosacea Functional medicine recognizes rosacea as a condition involving multiple interconnected systems: Gut microbiome Immune system regulation Nervous system activation Histamine signaling Skin barrier integrity Inflammatory cytokines Instead of viewing rosacea only through a dermatologic lens, functional medicine evaluates why the inflammatory response has become dysregulated

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