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Initial studies were conducted in animal models and progressed to human clinical observations, with particularly strong work on immune function, longevity markers, and circadian regulation

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Because a large number of comparisons were performed on the relative abundance data, main effect results from these analyses also underwent a BenjaminiHochberg false discovery rate (FDR) correction for multiple comparisons, and instances where a result was significant after this correction have been duly noted

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In the cells, cystine is reduced back to cysteine, which is an essential substrate for the synthesis of biomolecules such as proteins, glutathione (GSH) and Coenzyme A 3

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Fassbender, J., Holthoff, H

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