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Notably, over the subsequent 6 days, we observed a sustained body-weight-lowering effect after infusion of GLP-1MK-801, but not semaglutide, suggesting that the targeted inhibition of NMDA receptors in GLP-1 receptor-positive neurons might promote sustained changes to the defended level of adiposity

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In emergency treatment of acquired methemoglobinemia (typically using IV MB), the dose is weight-based, usually 1-2 mg/kg intravenously, which for an average adult (70 kg) is on the order of 70-140 mg administered once and can be repeated once if needed