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Depending on the drug, people can lose between 25%-50% of their lean body mass, Dr Gulati says

Moreover, the degree of benefit in reducing CVD risk factors and improving clinical outcomes increases with higher percentages of weight loss

The first GLP-1 receptor agonist, exenatide, was developed in 2005 and safely prescribed ever since

The 'receptor agonist' label that's often added refers to the way these drugs connect to and activate cell docking points called GLP-1 receptors, just like the real hormone

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Gene expression modulation is the main mechanism of TH by binding the active hormone T3 to specific nuclear receptors