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Previous studies in drug-nave rodents showed that activation of GLP-1-producing NTS neurons that project to the VTA transiently reduced food intake 28
New England Journal of Medicine, 393(1), 41-54
However, levels fall as we age, especially once we pass 40
In humans, the tongue has not yet been addressed as clinically relevant target for GLP-1 based therapies
This is detrimental, as muscle mass is metabolically active and contributes to many physiological processes
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