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Randomized, double-blind, placebo-controlled study of brodalumab, a human antiIL-17 receptor monoclonal antibody, in moderate to severe asthma

We showed that, unlike other conventional anti-cancer agents, 5-fluorouracil (5-FU) or cytosine arabinoside (ara-C), which are uracil and cytidine analogs, JMF4073 is not toxic to untransformed myeloid cells

Peptides are typically large, hydrophilic, and often charged, so they cross membranes poorly by passive diffusion

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