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Finally, an increase in free fatty oxidation and stimulation of ketogenesis has been proposed, thereby shifting cardiac substrate to more energy efficient use of fatty acids and ketones
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Further, it was explained that the appetite-reducing effects promoted by GLP-1R stimulation effectively reduce caloric intake by inducing satiety and delaying gastric emptying, making it a prime target to counter hyperglycemia and overeating [107]
The 5mg dose aligns with the formulations used across clinical peptide practices and provides a conservative entry point for assessing individual tolerance
doi:10.1016/j.autrev.2025.103864
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