when did retatrutide come out for weight loss: Study shows 30% body weight loss Retatrutide – new weight loss

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00:01:29 Vickie Danaher And we know that this follows the approval of the first oral GLP-1 agonist for this indication, oral semaglutide or Wegovy pill

Semaglutide targets the GLP-1 receptor, Tirzepatide activates both GLP-1 and GIP receptors, and Retatrutide is an investigational triple-action peptide that targets GLP-1, GIP, and glucagon receptors

According to NICE guideline NG28 on type 2 diabetes management and the specific NICE Technology Appraisal for tirzepatide, GLP-1 receptor agonists like Mounjaro may be considered as part of a comprehensive treatment strategy when glycaemic targets are not achieved with other therapies or when weight loss would provide significant clinical benefit

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Saha et al., 2022) found elevated GABA levels in autistic children compared to TDC