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The Two Mechanisms That Make GLP-1s Work for Arthritis GLP-1 medications change this in two ways: 1

Those with a BMI between 30 and 35 must also have one of the following: uncontrolled high blood pressure, prediabetes, a previous heart attack or stroke, blocked arteries in arms or legs with symptoms, chronic kidney disease at Stage 3a or higher, or diastolic heart failure

PMID: 17110467 | DOI: 10.1096/fj.06-6328com [22] Hermsdorff HH, Zulet M, Abete I, Martnez JA

These results were not surprising based on how the two drugs work, Dr