8-oxoguanine targeted by 8-oxoguanine dna glycosylase 1 (ogg1) is central to fibrogenic gene activation upon lung injury
Supplementation of LAC can induce neuroprotective and neurotrophic effects of the peripheral nervous system by increasing the level of brain-derived neurotrophic factor (BDNF), especially in the hippocampus and prefrontal cortex (9395)
Again we observed that rats responds HH in very short time (16h-24h), hence rodent model can be the best approach to study high altitude related illness at tissue level

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While important mechanistic insights were gained to decipher the glutaredoxin-catalyzed reduction of glutathione disulfide substrates, there are still major gaps in our understanding of the enzyme mechanism regarding the reduction of non-glutathione disulfide substrates