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Ruling out other causes and identifying and managing risk factors can also be important to minimize recurrences. In addition to long-lasting symptoms, its also important to seek professional treatment if you notice any warning signs of infection, including swelling, warmth in the affected area, fever, and fatigue

These include medications, topical treatments, injections,chemical peels, dermabrasion and microdermabrasion

J Cell Physiol 235(4):31573168 Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borz RM, Meliconi R (2014) Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1-stimulated production of chemokines and matrix-degrading enzymes in vitro

Vitamin B12 deficiency is most common in adults over 50, vegans and vegetarians, pregnant women, and those with chronic health conditions like Crohns disease, inflammatory bowel disease (IBS), or rheumatoid arthritis

Wang, M., Gao, Y., Li, G., & An, T

Br J Dermatol 183(2):396397