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GLP-1 agonists produce greater sustained weight loss, typically 1525% body weight reduction over 68 weeks in trials, compared to phentermine's 510% over 12 weeks
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To replicate specific mitochondrial GSH mechanisms and data from in vivo mice models, a mitochondrial compartment needs to be added
PMID 19318491
One contributing factor is that many studies evaluating treatments for cardiovascular prevention typically focus on common cardiovascular events such as coronary heart disease or stroke, often overlooking the reporting of MALE
Shang B, Liu Y, Juan J S, Liu Y
