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Emerging roles for the ER stress sensor IRE1 in metabolic regulation and disease

The first is extracellular matrix biology: fibroblast culture and rat wound-chamber work from the Maquart and Simeon groups reported that GHK-Cu stimulates collagen, glycosaminoglycan and small proteoglycan synthesis while simultaneously upregulating matrix metalloproteinase-2 and its tissue inhibitors, a combined synthesis-and-turnover signature unusual among matrix-active compounds

These enzymes are responsible for the metabolism of both exogenous and endogenous compounds

Multiple pregnancies: Women carrying more than one baby have higher micronutrient needs than women carrying one baby

doi: 10.1038/s41580-023-00689-6 13 NewtonKStrasserAKayagakiNDixitVM

Studies in mice with ovarian tumors showed that theanine plus doxorubicin was more effective in suppressing liver metastasis than doxorubicin alone