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Notably, chronic propionate accumulation downregulates cGMP-PKG, reducing contractility and promoting diastolic dysfunction with remodeling risk, particularly in female subjects (Park et al., 2023)

However, most carnitines, being quaternary ammonium cation complexes, exist in ionized states under RP-LC conditions, leading to weak chromatographic retention

doi: 10.1016/j.ghir.2004.03.006 14 JaffeCATurgeonDKFribergRDWatkinsPBBarkanAL

Dry beriberi affects the central nervous system (CNS) and peripheral nerves, whereas wet beriberi involves the cardiovascular system

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