Resistance training can involve lifting weights, using resistance bands, or doing bodyweight exercises that require strength (like squats, crunches, or pushups) Maintaining muscle mass helps prevent the decrease in daily calorie burn that comes from losing that lean tissue
The philosophy was that the larger gauge would stand a better chance of getting into the fat
Retatrutide is an investigational injectable medicine from Eli Lilly
References : Office of Dietary Supplements, NIH
Pegbelfermin (BMS-986036), PEGylated FGF21, in patients with obesity and type 2 diabetes: results from a randomized phase 2 study
The study found the drug worked to slow down loss of kidney function, lowered systolic blood pressure, and reduced body weight among participants