Further research is needed to investigate GSH dynamics longitudinally, validate these observations in independent cohorts, explore the therapeutic potential of antioxidant interventions, and confirm these findings in multicenter studies
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doi: 10.1016/j.clnu.2016.11.017 299 MalekiARahimiRMalekiS
Karlberg, S., Tiitinen, A
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Upon recognizing and binding lipopolysaccharide (LPS), mouse caspase-11 or human caspase-4/5 proteolytically cleaves GSDMD, leading to plasma membrane rupture (164)