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doi:10.1186/s13104-015-1437-9
Chen found in human melanoma cells that silencing iPLA2 would enhance the sensitivity to p53-mediated ferroptosis without significant effects on cells that usually express iPLA2, suggesting that iPLA2 can inhibit p53-mediated ferroptosis, and p53-driven ferroptosis is independent of GPX4 [41]
Therefore, it is prescribed to patients who have type 2 diabetes and obesity as a blood glucose management therapy, along with being a weight loss medication
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