It could point to several things: A different cause: your fatigue might stem from thyroid problems, iron deficiency, or sleep apnea rather than B12
Inflammation: Low glutathione levels contribute to chronic inflammation, which drives many age-related conditions, including skin aging, cardiovascular issues, and cognitive decline
During the evolution of Cyanobacteria and Proteobacteria, GSH-dependent ROS detoxification systems incorporated enzymes that play crucial roles in these mechanisms and use GSH as a cofactor, such as GSH peroxidases, GSH reductases, glutaredoxins, and GSH-S-transferases [41]
If you want a deeper look at how liposomal delivery supports absorption, our All About Liposomes guide is a helpful place to start
It is therefore an integrated metabolic readout rather than a direct ROS meter
A 12-week cycle pairs with a 4-6 week break