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For confirmed B12 deficiency without neurological involvement , the standard regimen comprises 1 mg hydroxocobalamin intramuscularly three times weekly for two weeks, followed by maintenance doses every two to three months for those with irreversible causes like pernicious anaemia

It may sound simple to decide the right treatment strategy, but the big question is how to identify patients able to absorb vitamin B12 provided by food or a vitamin pill, as compared to those who have lost the capacity to absorb vitamin B12

The response is cumulative, building across the 4 doses and continuing into the weeks after the final injection

Mitochondrial Pathways

This helps it get absorbed better

However, B12 injections are not a treatment for insomnia, depression, or anxiety on their own