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Apply a small amount evenly to face and neck

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This can occur due to the enlargement of the left ventricle (dilated cardiomyopathy), abnormal thickening of the heart muscle (hypertrophic cardiomyopathy), or stiffening of the heart muscle that prevents it from adequately expanding and filling with blood (restrictive cardiomyopathy)

Its found naturally in your blood, saliva, and tissues