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Metformin affects gut microbiome composition and function and circulating short-chain fatty acids: a randomized trial

To investigate whether the cutoff of glucose at 3.1 mmol/L impacts the data analysis, we performed a sensitivity analysis using different cut-offs for glucose between 2.7 and 3.4 mmol/L

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It also impacts daytime function brain fog, headaches, mood changes, and that I slept 8 hours but Im still exhausted feeling