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These medications work by binding to receptors in the brain, pancreas, and gastrointestinal tract, creating multiple physiological effects that support weight reduction

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But in the short run, GI side effects like Nausea, vomiting, and diarrhea can leave you dehydrated, and dehydration can cause a temporary drop in kidney function that shows up as a rising creatinine and a falling eGFR

Auto poisoning of the respiratory chain by a quorum sensing regulated molecule favors biofilm formation and antibiotic tolerance

While these medications are not primarily classified as hormonal therapies, their metabolic effects inevitably intersect with endocrine function, particularly in patients with obesity and insulin resistanceconditions known to disrupt multiple hormonal axes