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10.1111/dom.15333 18 IidaA.SeinoY.FukamiA.MaekawaR.YabeD.ShimizuS.et al (2016)

the NNMT inhibitor literature does not, with every published in-vivo study of 5-Amino-1MQ conducted in rodents and no NNMT inhibitor approved in any jurisdiction

It is important to mention that on all testing days, the group receiving the higher dose of Dihexa experienced performance that was indistinguishable from the control group administered only vehicle compounds [2]

The most frequent TEAEs across the two studies were nausea, vomiting, decreased appetite and injection site erythema

Dosages in animal studies: In the vast majority of preclinical studies, the doses used in rats range between 10 g/kg and 10 ng/kg of body weight, administered intraperitoneally or orally