The Phase 3 trials, TRIUMPH and TRANSCEND, are underway and not yet published
With declining DHEA-S levels, cortisol levels remain constant, resulting in an increased cortisol/DHEA-S ratio
Some tiredness can be part of the adjustment period on GLP-1 medicines especially after dose changes but you should get medical advice sooner rather than later if symptoms are severe, persistent, or escalating
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If a person notices signs like persistent stomach pain, severe nausea, or any yellowing of the skin, they should seek medical attention right away
10.3390/ph17060736 2 AhmannA