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This treatment successfully induced senescence, as evidenced by a significant increase in SA--gal activity

In summary, 25-OHC, NRF2, SPY1, and MPO regulate neuronal ferroptosis and lipid peroxidation, thereby participating in the pathological development of ALS

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Increased autophagy was apparent, as reflected by increased LC3 expression, autophagic vacuoles, and autophagic flux

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