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Internal standards (e.g., isotopically labeled peptides) may be needed to compensate for these matrix effects, ensuring precise and accurate quantification in LC-MS analyses

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Detection windows can vary based on: Type of peptide Dosage Frequency of use Metabolism Testing sensitivity Some peptides may only be detectable for a short period, while others may remain detectable for much longer

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Here is what happened: Absolute grip strength decreased slightly with semaglutide compared to untreated obese mice