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Insulin remains the preferred choice only when GLP-1 drugs are contraindicated, unaffordable, or insufficient alone, or when the patient has Type 1 diabetes

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Cognitive manifestations include depression, irritability, and anxiety, while GI manifestations encompass constipation, dysphagia, nausea, and prolonged intestinal transit time (Pfeiffer, 2003

It is imperative for patients to have thorough discussions about these with their healthcare providers

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