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Weight loss through any means typically reduces hsCRP, but the magnitude of reduction with GLP-1 based therapies appears to exceed what weight loss alone would predict

Scientists have also explored L-Carnitine in exercise physiology and muscle metabolism studies

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The proportion of patients achieving NASH resolution in the absence of fibrosis progression was 40%, 36%, and 59% for the 0.1, 0.2, and 0.4 mg semaglutide arms, respectively, whereas the corresponding rate in the placebo arm was 17% (Newsome et al., 2021)