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Each additional receptor contributes a distinct metabolic effect: GIP modulates insulin secretion and adipose handling, glucagon contributes to energy expenditure [3][4]

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Another medication class, DPP-4 inhibitors, works by preventing the breakdown of your body's natural GLP-1, though with more modest effects

2013;8(1):e54431

Retatrutide 10 mg is used in experimental settings examining early metabolic imbalance, insulin resistance pathways, and systemic energy regulation

Factors such as age, heart failure, and a previous stroke did not alter the findings