wegovy is tirzepatide Weight loss drugs like Mounjaro (Tirzepatide) and (Semaglutide) are changing the way we approach obesity management. But patients often ask: ✔️ How do these medicines work? ✔️ Who should use them Switching between weight-loss medications -

Evidence synthesis: We integrate RCT evidence on weight and metabolic outcomes with exploratory findings on reproductive outcomes, highlighting key effect modifiers (baseline obesity/IR phenotype, concomitant metformin, and follow-up window)

doi: 10.3390/nu10030297 120 BabbsRKSunXFelstedJChouinard-DecorteFVeldhuizenMGSmallDM

Posology and Method of Administration: The starting dose is 0.25 mg once a week for the first 4 weeks

Most patients begin tirzepatide at 2.5 mg injected once weekly, the dose used in initial clinical trials to establish safety and tolerability

This medication works by enhancing insulin secretion, suppressing glucagon release, and slowing gastric emptyingmechanisms that contribute to improved glycemic control and weight loss

Alcohol can worsen dehydration during hot weather, and some semaglutide side effects like dizziness and fatigue may intensify in the heat