GLP-1 is a naturally occurring hormone found in the small intestine that works to release insulin from the pancreas
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Methods: Narrative review
GLP-1 receptors are expressed in the heart muscle cells, immune system cells in the heart, and in the lining of blood vessels.[ref] GLP-1 RAs have been shown to help in heart failure and also to have beneficial effects on heart rhythm.[ref] Related article : Cardiovascular disease genetic risk factors Cancer Research: Retatrutide, a GLP-1/GIP/GCG triple agonist, has recently been shown to reduce pancreatic tumor mass in animals
demonstrated that the most popular drugs used for PCT were clomiphene (77%), tamoxifen (75%), and hCG (74%) (Smit et al., 2021), tamoxifen (70%), clomiphene citrate (54%), and hCG (55%) were mostly used as PCT drugs
Another involves stepping from 1mg to 1.5mg before jumping to 2mg, creating an intermediate tier that the clinical trials did not formally test but that some researchers implement based on tolerability assessments