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Endogenous hydrogen peroxide up-regulates the expression of nitric oxide synthase in the kidney of SHR
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We chose the Akita mouse model to test our hypothesis for multiple reasons
In this step the cytosolic, NADH-derived reducing equivalents become available to the NADH dehydrogenase (complex I) of the inner mitochondrial membrane and are oxidized, giving rise to approximately 2.5 moles of ATP as described earlier
Glutathione is a tripeptide antioxidant made up of three amino acids: glycine, cysteine, and glutamic acid
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