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Administered subcutaneously, its injectable form is rapidly absorbed and distributed to metabolically active tissues, where it specifically binds and inhibits NNMT catalytic activity without interfering with other enzymes in the nicotinamide pathway or NAD+ synthesis

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Why a normal or high total B12 can coexist with cellular deficiency Total B12 measures what is in the blood, not what has reached the cells, so a high or normal value does not rule out a functional shortfall

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