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Ristori MV, Mortera SL, Marzano V, Guerrera S, Vernocchi P, Ianiro G, Gardini S, Torre G, Valeri G, Vicari S, Gasbarrini A, Putignani L (2020) Proteomics and metabolomics approaches towards a functional insight onto AUTISM spectrum disorders: phenotype stratification and biomarker discovery

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Even though the exact structure of the mPTP, as well as its assembly kinetics, is still unknown, interesting findings suggested that dissociation of F 1 F O ATP synthase dimers 45 and the c subunit pore-forming part 46 have an important role in mitochondrial permeability transition (mPT) and constitute a valid therapeutic approach in pathologies subjected to widespread cell death 47,48

DOI: 10.1073/pnas.78.8.4767 52