2006 DOI: 10.1002/jor.20096 PMID: 16583442 Read on PubMed Current Pharmaceutical Design Fistulas Healing
In three nested casecontrol studies from England and Wales, involving 440,089 patients with T2DM and without ASCVD treated with non-insulin glucose-lowering medication, combined SGLT2i and GLP-1RA therapy used for primary prevention was associated with 30% lower odds of MACE (defined as myocardial infarction/acute coronary syndrome, stroke/transient ischemic attack, and/or cardiovascular death) compared with other combination regimens (OR, 0.70
When combined with the appetite-suppressing effects of GLP-1 and the metabolic enhancement from GIP, this creates a three-pronged approach to weight management that attacks the problem from multiple angles simultaneously
Keep in mind however, that it does take at least a week or more to start to notice a difference in how you feel
Problems with this can be upsetting and worrying
This percentage can be higher if someone isnt physically active