Despite the protective role of autophagy against epilepsy, though its role in SE is perplexing and might be a double-edged sword, may be detrimental or harmful
ES NDs effectively reduce the abnormal accumulation of Fe 2+ , GPX4 inactivation, and lipid peroxidation in chondrocytes, thereby improving the metabolic disorders of chondrocytes caused by ferroptosis, and show significant therapeutic effects in alleviating OA
Koca et al
The execution of ferroptosis is governed by a tightly regulated network of antioxidant defence systems, among which the GPX4-GSH axis plays a central role
In studies examining exercise performance, combined supplementation of vitamin C and glutathione demonstrated: [10] Decreased heart rate during exercise Reduced carbon dioxide output Improved skeletal muscle oxygenation Attenuation of exercise-induced oxidative stress markers These benefits weren't observed to the same degree when either antioxidant was supplemented alone, underscoring the synergistic relationship
Egging D, van Vlijmen-Willems I, van Tongeren T, et al