The thing is, the company had already submitted its application for approval before these results were released, and that application is based on earlier studies showing strong weight loss and blood sugar improvements on their own
Nature 586 , 429433 (2020)
Acetyl-L-Carnitine Supplementation and the Treatment of Depressive Symptoms: A Systematic Review and Meta-Analysis
Additionally, aspiration risk has been raised as a concern primarily in perioperative settings due to delayed gastric emptying, leading to recent multi-society anesthesia guidelines addressing GLP-1 receptor agonist management before procedures
ECG monitoring may be necessary, particularly if there are cardiac risk factors or if these medications are used with other QT-prolonging drugs (including ondansetron)
Inflammation modulation research helps explain why many users report rapid pain reduction even before significant structural healing occurs