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Annu Rev Pharmacol Toxicol (2011) 51:16987

Human studies

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Instead, laser energy is used to heat the fat cells underneath the skins surface without disrupting the outer dermal layers

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Patients discontinuing GLP-1 medications should monitor for signs of gallbladder problems (severe abdominal pain, especially after meals), pancreatitis (persistent severe abdominal pain, sometimes with vomiting), or significant hyperglycemia