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reductions in waist circumference were associated with lower MACE risk and accounted for approximately one-third of the treatment effect, although this likely reflects a risk marker rather than a proven causal mediator

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Like Saxenda (liraglutide), Ozempic (semaglutide) and WeGovy (semaglutide) have been shown to be effective in reducing HbA1c levels and promoting weight loss in people with type 2 diabetes