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[19] Removing mercury fillings can reduce thyroid peroxidase antibodies (TPO antibodies) in the blood

Here we investigated the potential interactions between APR-246/MQ and Trx1 and Grx1, and found that reaction of MQ with both Trx1 and Grx1 was associated with loss of free thiols in both proteins

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doi: 10.1038/379069a0 13 DunganKMPovedanoSTForstTGonzalezJGAtissoCSeallsWet al

They may be experiencing anaphylaxis, which is a severe allergic reaction

However, it is recommended to perform a patch test before initial use to check for any adverse reactions