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Develop and validate standard operating procedures (SOPs) for reconstitution that specify exact techniques, solvent sources, equipment requirements, and quality checks
Glucagon-like peptide-1 (GLP-1) receptor agonists represent a class of medications increasingly prescribed in the UK for type 2 diabetes management and, more recently, for weight management in adults with obesity
Rarer side effects must be monitored by a doctor at hand
As a result, other drugmakers are working on generic versions
SOUL Published in the New England Journal of Medicine , SOUL was a double-blind, placebo-controlled, event-driven superiority trial, enrolling 9650 participants who were randomised to receive oral semaglutide (up to 14 mg once daily) or placebo, alongside standard care for diabetes and CVD (McGuire et al, 2025)
10.1136/bmj.m3684 130 ShimanoH.SatoR
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