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Since its introduction, 5-Amino-1MQ has become a valuable research tool within metabolic science, obesity research, and cellular physiology investigations aimed at understanding the role of NNMT in human biology

SARS-CoV-2 infection dysregulates NAD metabolism

5-Amino-1MQ is a substrate-mimetic inhibitor occupying the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)