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Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

Studies show that inflammation in the prostate may expand the pool of progenitor-like stem cells that are prone to malignant transformation [ 11 ]

Nox family NADPH oxidases: molecular mechanisms of activation

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The production of glutathione is an active process that requires energy and raw materials