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Figure 1 Figure 2 The discovery of the second incretin, GLP-1, originated from observations in 1982 that anglerfish proglucagon mRNA contained coding sequences of glucagon-related peptide, flanked by pairs of basic amino acids characteristic of the sites cleaved during post-translational processing of prohormones ( Figure 1 Section A]
At the molecular level, Sermorelin is thought to bind to GHRH receptors located on pituitary somatotrophs
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doi:10.1186/s13098-021-00672-1 Lee Y, Berglund ED, XinXin Y, et al
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