The presence of selenate was observed in human CSF (Vinceti et al., 2013b, 2019
In todays population, heavy metal toxicity is ubiquitous, along with exposure to many other endogenous neurotoxic chemicals, which means that inevitably the biochemical individuality to deal with these toxins may be the major determinate of disease
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In addition, carnitine also depletes mitochondrial and ER Ca 2+ storage by activating phospholipase C, further increasing the intracellular Ca 2+ concentration
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