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Consequently, oxidative damage induced by lipid peroxidation directly impairs sperm motility and fertilization potential, thereby contributing to infertility

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The elevated H 2 O 2 concentration drives the balance in the GPX and GR reactions towards GSSG thus lowering the [GSH]/[GSSG] ratio

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GSH levels increase during oocyte maturation in the ovary, reaching a peak at the metaphase II (M II) stage []