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GLP-3 RT is studied as a tri-agonist compound, designed to interact with three receptor systems GLP-1, GIP, and glucagon simultaneously
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Furthermore, it appears to increase GLP1R expression (promoting more GLP-1 receptors) and reduce DPP4 expression (maintaining more active GLP-1)
Retatrutide differs from semaglutide and tirzepatide because it targets three pathways (GLP-1, GIP, and glucagon)
To maximize the benefits of these drugs, pair them with lifestyle changes like a well-balanced diet and regular exercise
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